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Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro

BACKGROUND AND PURPOSE: Several selective oestrogen receptor modulators (SERMs) with oestrogen agonist effects in bone cells and without increased risk of breast and endometrial cancer have been developed. Here, we have investigated the effects of different types of SERMs on osteoclast differentiati...

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Detalhes bibliográficos
Main Authors: Michael, H, Härkönen, P L, Kangas, L, Väänänen, H K, Hentunen, T A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013975/
https://ncbi.nlm.nih.gov/pubmed/17420779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707232
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