Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro

BACKGROUND AND PURPOSE: Several selective oestrogen receptor modulators (SERMs) with oestrogen agonist effects in bone cells and without increased risk of breast and endometrial cancer have been developed. Here, we have investigated the effects of different types of SERMs on osteoclast differentiati...

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Autores principales: Michael, H, Härkönen, P L, Kangas, L, Väänänen, H K, Hentunen, T A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013975/
https://ncbi.nlm.nih.gov/pubmed/17420779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707232
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