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N-Me, a long range oncogenic enhancer in T-cell acute lymphoblastic leukemia

Efforts to identify and annotate cancer driver genetic lesions have been almost exclusively focused on the analysis of protein coding genes. Here we identify a new long-range acting MYC enhancer controlled by NOTCH1, targeted by recurrent chromosomal duplications in human T-cell acute lymphoblastic...

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Autors principals: Herranz, Daniel, Ambesi-Impiombato, Alberto, Palomero, Teresa, Schnell, Stephanie A., Belver, Laura, Wendorff, Agnieszka A., Xu, Luyao, Castillo-Martin, Mireia, Llobet-Navás, David, Cardo, Carlos Cordon, Clappier, Emmanuelle, Soulier, Jean, Ferrando, Adolfo A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192073/
https://ncbi.nlm.nih.gov/pubmed/25194570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3665
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