Synergistic Effect of Local Endothelial Shear Stress and Systemic Hypercholesterolemia on Coronary Atherosclerotic Plaque Progression and Composition in Pigs

BACKGROUND: Systemic risk factors and local hemodynamic factors both contribute to coronary atherosclerosis, but their possibly synergistic inter-relationship remains unknown. The purpose of this natural history study was to investigate the combined in-vivo effect of varying levels of systemic hyper...

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Autors principals: Koskinas, Konstantinos C., Chatzizisis, Yiannis S., Papafaklis, Michail I., Coskun, Ahmet U., Baker, Aaron B., Jarolim, Petr, Antoniadis, Antonios, Edelman, Elazer R., Stone, Peter H., Feldman, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191915/
https://ncbi.nlm.nih.gov/pubmed/24148915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2013.10.021
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