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Linear Motif-Mediated Interactions Have Contributed to the Evolution of Modularity in Complex Protein Interaction Networks

The modular architecture of protein-protein interaction (PPI) networks is evident in diverse species with a wide range of complexity. However, the molecular components that lead to the evolution of modularity in PPI networks have not been clearly identified. Here, we show that weak domain-linear mot...

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Detalhes bibliográficos
Main Authors: Kim, Inhae, Lee, Heetak, Han, Seong Kyu, Kim, Sanguk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191887/
https://ncbi.nlm.nih.gov/pubmed/25299147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003881
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