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Population-Based Pharmacokinetic Modeling of Vancomycin in Children with Renal Insufficiency

BACKGROUND: Vancomycin dosing to achieve the area-under-the-curve to minimum inhibitory concentration (AUC/MIC) target of ≥ 400 in children with renal insufficiency is unknown. Our objectives were to compare vancomycin clearance (CL) and initial dosing in children with normal and impaired renal func...

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Detalhes bibliográficos
Main Authors: Le, Jennifer, Vaida, Florin, Nguyen, Emily, Adler-Shohet, Felice C., Romanowski, Gale, Kim, Jiah, Vo, Tiana, Capparelli, Edmund V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191860/
https://ncbi.nlm.nih.gov/pubmed/25309945
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