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Multiscale conformational heterogeneity in the protein-binding domains of staphylococcal protein A: Possible determinant of functional plasticity()
The Staphylococcus aureus virulence factor staphylococcal protein A (SpA) is a major contributor to bacterial evasion of the host immune system, through high-affinity binding to host proteins such as antibodies. SpA includes five small three-helix-bundle domains (E-D-A-B-C) separated by conserved fl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191857/ https://ncbi.nlm.nih.gov/pubmed/25295398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.08.014 |
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