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Selective filtering defect at the axon initial segment in Alzheimer’s disease mouse models

Axon pathology has been widely reported in Alzheimer’s disease (AD) patients and AD mouse models. Herein we report that increased miR-342–5p down-regulates the expression of ankyrin G (AnkG), a protein known to play a critical role in establishing selective filtering machinery at the axon initial se...

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Detalhes bibliográficos
Main Authors: Sun, Xiaqin, Wu, Yu, Gu, Mingxue, Liu, Zhuo, Ma, Yuanlin, Li, Jun, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191768/
https://ncbi.nlm.nih.gov/pubmed/25232037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411837111
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