Axon initial segment dysfunction in epilepsy

The axon initial segment (AIS) contains the site of action potential initiation and plays a major role in neuronal excitability. AIS function relies on high concentrations of different ion channels and complex regulatory mechanisms that orchestrate molecular microarchitecture. We review recent evide...

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Detalhes bibliográficos
Main Authors: Wimmer, Verena C, Reid, Christopher A, So, Eva Y-W, Berkovic, Samuel F, Petrou, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Special Section Reviews: Neurological Channelopathies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901971/
https://ncbi.nlm.nih.gov/pubmed/20375142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188417
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