Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA

Dengue virus nonstructural protein 3 (NS3) is a multifunctional protein formed by a superfamily-2 RNA helicase linked to a protease domain. In this work, we report results from in vitro experiments designed to determine the oligomeric state of dengue virus NS3 helicase (NS3h) and to characterize fun...

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Библиографические подробности
Главные авторы: Gebhard, Leopoldo G., Incicco, J. Jeremías, Smal, Clara, Gallo, Mariana, Gamarnik, Andrea V., Kaufman, Sergio B.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Nucleic Acid Enzymes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191397/
https://ncbi.nlm.nih.gov/pubmed/25223789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku812
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