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The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes
Chromatin constitutes a repressive barrier to the process of ligand-dependent transcriptional activity of nuclear receptors. Nucleosomes prevent the binding of estrogen receptor α (ERα) in absence of ligand and thus represent an important level of transcriptional regulation. Here, we show that in br...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191390/ https://ncbi.nlm.nih.gov/pubmed/25223786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku791 |
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