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A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions

Identification of three-dimensional (3D) interactions between regulatory elements across the genome is crucial to unravel the complex regulatory machinery that orchestrates proliferation and differentiation of cells. ChIA-PET is a novel method to identify such interactions, where physical contacts b...

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Detalles Bibliográficos
Main Authors: Paulsen, Jonas, Rødland, Einar A., Holden, Lars, Holden, Marit, Hovig, Eivind
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191384/
https://ncbi.nlm.nih.gov/pubmed/25114054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku738
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