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Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion

In humans, vWF levels predict the risk of myocardial infarction and thrombosis; however, the factors that influence vWF levels are not completely understood. Recent genome-wide association studies (GWAS) have identified syntaxin-binding protein 5 (STXBP5) as a candidate gene linked to changes in vWF...

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Bibliographic Details
Main Authors: Zhu, Qiuyu, Yamakuchi, Munekazu, Ture, Sara, de la Luz Garcia-Hernandez, Maria, Ko, Kyung Ae, Modjeski, Kristina L., LoMonaco, Michael B., Johnson, Andrew D., O’Donnell, Christopher J., Takai, Yoshimi, Morrell, Craig N., Lowenstein, Charles J.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191049/
https://ncbi.nlm.nih.gov/pubmed/25244095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71245
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