Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion

Ovarian cancer (OvCa) metastasizes to organs in the abdominal cavity, such as the omentum, which are covered by a single layer of mesothelial cells. Mesothelial cells are generally thought to be “bystanders” to the metastatic process and simply displaced by OvCa cells to access the submesothelial ex...

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Autori principali: Kenny, Hilary A., Chiang, Chun-Yi, White, Erin A., Schryver, Elizabeth M., Habis, Mohammed, Romero, Iris L., Ladanyi, Andras, Penicka, Carla V., George, Joshy, Matlin, Karl, Montag, Anthony, Wroblewski, Kristen, Yamada, S. Diane, Mazar, Andrew P., Bowtell, David, Lengyel, Ernst
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191043/
https://ncbi.nlm.nih.gov/pubmed/25202979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74778
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