CD45 ligation expands Tregs by promoting interactions with DCs

Regulatory T cells (Tregs), which express CD4 and FOXP3, are critical for modulating the immune response and promoting immune tolerance. Consequently, methods to expand Tregs for therapeutic use are of great interest. While transfer of Tregs after massive ex vivo expansion can be achieved, in vivo e...

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Bibliografische gegevens
Hoofdauteurs: Camirand, Geoffrey, Wang, Ying, Lu, Yuning, Wan, Yisong Y., Lin, Yan, Deng, Songyan, Guz, Galip, Perkins, David L., Finn, Patricia W., Farber, Donna L., Flavell, Richard A., Shlomchik, Warren D., Lakkis, Fadi G., Rudd, Christopher E., Rothstein, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191025/
https://ncbi.nlm.nih.gov/pubmed/25202978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74087
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