Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature

Retinal and choroidal neovascularization (NV) and vascular leakage contribute to visual impairment in several common ocular diseases. The angiopoietin/TIE2 (ANG/TIE2) pathway maintains vascular integrity, and negative regulators of this pathway are potential therapeutic targets for these diseases. H...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shen, Jikui, Frye, Maike, Lee, Bonnie L., Reinardy, Jessica L., McClung, Joseph M., Ding, Kun, Kojima, Masashi, Xia, Huiming, Seidel, Christopher, Silva, Raquel Lima e, Dong, Aling, Hackett, Sean F., Wang, Jiangxia, Howard, Brian W., Vestweber, Dietmar, Kontos, Christopher D., Peters, Kevin G., Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191011/
https://ncbi.nlm.nih.gov/pubmed/25180601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74527
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados