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Maternally transmitted mitochondrial DNA mutations can reduce lifespan
We recently showed that germline transmission of mitochondrial DNA mutations via the oocyte cause aggravation of aging phenotypes in prematurely aging mtDNA mutator (PolgA(mut/mut)) mice. We discovered that 32% of these mice also exhibit stochastic disturbances of brain development, when maternal mt...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190956/ https://ncbi.nlm.nih.gov/pubmed/25299268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06569 |
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