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An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein

Human papillomavirus 16 (HPV16) is a high-risk DNA tumour virus which is the primary causative agent of cervical cancer. Cell transformation arises from deregulated expression of the E6 and E7 oncogenes. E6 has been shown to bind a number of cellular proteins, including p53 and proteins containing a...

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書誌詳細
主要な著者: Belyaeva, Tamara A., Nicol, Clare, Cesur, Özlem, Travé, Gilles, Blair, George Eric, Stonehouse, Nicola J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190555/
https://ncbi.nlm.nih.gov/pubmed/25062098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6031553
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