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An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
Human papillomavirus 16 (HPV16) is a high-risk DNA tumour virus which is the primary causative agent of cervical cancer. Cell transformation arises from deregulated expression of the E6 and E7 oncogenes. E6 has been shown to bind a number of cellular proteins, including p53 and proteins containing a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190555/ https://ncbi.nlm.nih.gov/pubmed/25062098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6031553 |
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