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Improving Co-Amorphous Drug Formulations by the Addition of the Highly Water Soluble Amino Acid, Proline

Co-amorphous drug amino acid mixtures were previously shown to be a promising approach to create physically stable amorphous systems with the improved dissolution properties of poorly water-soluble drugs. The aim of this work was to expand the co-amorphous drug amino acid mixture approach by combini...

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Detalhes bibliográficos
Main Authors: Jensen, Katrine Tarp, Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190527/
https://ncbi.nlm.nih.gov/pubmed/25025400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics6030416
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