Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep

INTRODUCTION: Acute kidney injury (AKI) is a common and feared complication of sepsis. The pathogenesis of sepsis-induced AKI is largely unknown, and therapeutic interventions are mainly supportive. In the present study, we tested the hypothesis that pharmacological inhibition of Toll-like receptor...

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Autori principali: Fenhammar, Johan, Rundgren, Mats, Hultenby, Kjell, Forestier, Jakob, Taavo, Micael, Kenne, Ellinor, Weitzberg, Eddie, Eriksson, Stefan, Ozenci, Volkan, Wernerson, Annika, Frithiof, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190385/
https://ncbi.nlm.nih.gov/pubmed/25182709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0488-y
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