Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy and Puromycin Aminonucleoside Nephrosis

BACKGROUND/AIMS: The transmembrane proteins Neph1 and nephrin form a complex in the slit diaphragm (SD) of podocytes. As recent studies indicate an involvement of this complex in the polymerization of the actin cytoskeleton and proteinuria, we wanted to study the subcellular localization of Neph1 in...

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Bibliografiske detaljer
Main Authors: Hulkko, Jenny, Patrakka, Jaakko, Lal, Mark, Tryggvason, Karl, Hultenby, Kjell, Wernerson, Annika
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2014
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202611/
https://ncbi.nlm.nih.gov/pubmed/25404935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365091
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