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Bent bone dysplasia syndrome reveals nucleolar activity for FGFR2 in ribosomal DNA transcription

Fibroblast growth factor receptor 2 (FGFR2) promotes osteoprogenitor proliferation and differentiation during bone development, yet how the receptor elicits these distinct cellular responses remains unclear. Analysis of the FGFR2-skeletal disorder bent bone dysplasia syndrome (BBDS) demonstrates tha...

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Detalhes bibliográficos
Main Authors: Neben, Cynthia L., Idoni, Brian, Salva, Joanna E., Tuzon, Creighton T., Rice, Judd C., Krakow, Deborah, Merrill, Amy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189901/
https://ncbi.nlm.nih.gov/pubmed/24908667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu282
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