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Nuclear FGFR2 regulates musculoskeletal integration within the developing limb

BACKGROUND: Bent Bone Dysplasia Syndrome (BBDS), a congenital skeletal disorder caused by dominant mutations in Fibroblast growth factor receptor 2 (FGFR2), is characterized by bowed long bones within the limbs. We previously showed that the FGFR2 mutations in BBDS enhance nuclear and nucleolar loca...

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Detalhes bibliográficos
Publicado no:Dev Dyn
Main Authors: Salva, Joanna E., Roberts, Ryan R., Stucky, Taylor S., Merrill, Amy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474847/
https://ncbi.nlm.nih.gov/pubmed/30620790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.9
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