Coding variants in TREM2 increase risk for Alzheimer's disease

The triggering receptor expressed on myeloid 2 (TREM2) is an immune phagocytic receptor expressed on brain microglia known to trigger phagocytosis and regulate the inflammatory response. Homozygous mutations in TREM2 cause Nasu–Hakola disease, a rare recessive form of dementia. A heterozygous TREM2...

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Detaylı Bibliyografya
Asıl Yazarlar: Jin, Sheng Chih, Benitez, Bruno A., Karch, Celeste M., Cooper, Breanna, Skorupa, Tara, Carrell, David, Norton, Joanne B., Hsu, Simon, Harari, Oscar, Cai, Yefei, Bertelsen, Sarah, Goate, Alison M., Cruchaga, Carlos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Association Studies Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189899/
https://ncbi.nlm.nih.gov/pubmed/24899047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu277
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