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Lipopolysaccharide induced conversion of recombinant prion protein
The conformational conversion of the cellular prion protein (PrP(C)) to the β-rich infectious isoform PrP(Sc) is considered a critical and central feature in prion pathology. Although PrP(Sc) is the critical component of the infectious agent, as proposed in the “protein-only” prion hypothesis, cellu...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189894/ https://ncbi.nlm.nih.gov/pubmed/24819168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.28939 |
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