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14-3-3 and aggresome formation: Implications in neurodegenerative diseases
Protein misfolding and aggregation underlie the pathogenesis of many neurodegenerative diseases. In addition to chaperone-mediated refolding and proteasomal degradation, the aggresome-macroautophagy pathway has emerged as another defense mechanism for sequestration and clearance of toxic protein agg...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189886/ https://ncbi.nlm.nih.gov/pubmed/24549097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.28123 |
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