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Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL
Non-Hodgkin lymphomas (NHLs) account for 4% of all malignancies. 5-year survival rate increased to 50% with new treatment modalities, however there is need for new effective treatment for the more aggressive, relapsing forms. Recently, CTLA4-FasL, that can bind to B7 and Fas receptor (Fas), was show...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
BioMed Central
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189725/ https://ncbi.nlm.nih.gov/pubmed/25227919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0064-6 |
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