An evidence-based review of ixazomib citrate and its potential in the treatment of newly diagnosed multiple myeloma

Proteasome inhibition represents one of the more important therapeutic targets in the treatment of multiple myeloma (MM), since by suppressing nuclear factor-κB activity, which promotes myelomagenesis, it makes plasma cells susceptible to proapoptotic signals. Bortezomib, the first proteasome inhibi...

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Detaylı Bibliyografya
Asıl Yazarlar: Offidani, Massimo, Corvatta, Laura, Caraffa, Patrizia, Gentili, Silvia, Maracci, Laura, Leoni, Pietro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2014
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189713/
https://ncbi.nlm.nih.gov/pubmed/25302026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S49187
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