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An evidence-based review of ixazomib citrate and its potential in the treatment of newly diagnosed multiple myeloma
Proteasome inhibition represents one of the more important therapeutic targets in the treatment of multiple myeloma (MM), since by suppressing nuclear factor-κB activity, which promotes myelomagenesis, it makes plasma cells susceptible to proapoptotic signals. Bortezomib, the first proteasome inhibi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189713/ https://ncbi.nlm.nih.gov/pubmed/25302026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S49187 |
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