α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo

Cratoxylum arborescens is an equatorial plant belonging to the family Guttiferae. In the current study, α-Mangostin (AM) was isolated and its cell death mechanism was studied. HCS was undertaken to detect the nuclear condensation, mitochondrial membrane potential, cell permeability, and the release...

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Autori principali: Ibrahim, Mohamed Yousif, Hashim, Najihah Mohd, Mohan, Syam, Abdulla, Mahmood Ameen, Kamalidehghan, Behnam, Ghaderian, Mostafa, Dehghan, Firouzeh, Ali, Landa Zeenelabdin, Arbab, Ismail Adam, Yahayu, Maizatulakmal, Lian, Gwendoline Ee Cheng, Ahmadipour, Fatemeh, Ali, Hapipah Mohd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189707/
https://ncbi.nlm.nih.gov/pubmed/25302018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S66105
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