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Diverse modes of genomic alteration in hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is a heterogeneous disease with high mortality rate. Recent genomic studies have identified TP53, AXIN1, and CTNNB1 as the most frequently mutated genes. Lower frequency mutations have been reported in ARID1A, ARID2 and JAK1. In addition, hepatitis B virus...
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| Autori principali: | , , , , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189592/ https://ncbi.nlm.nih.gov/pubmed/25159915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0436-9 |
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