Polyphenols Isolated from Allium cepa L. Induces Apoptosis by Induction of p53 and Suppression of Bcl-2 through Inhibiting PI3K/Akt Signaling Pathway in AGS Human Cancer Cells

BACKGROUND: The extract of Allium cepa Linn is commonly used as adjuvant food for cancer therapy. We assumed that it includes a potential source of anti-cancer properties. METHODS: We investigated anti-cancer effects of polyphenols extracted from lyophilized A. cepa Linn (PEAL) in AGS human cancer c...

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Main Authors: Lee, Won Sup, Yi, Sang Mi, Yun, Jeong Won, Jung, Ji Hyun, Kim, Dong Hoon, Kim, Hye Jung, Chang, Seong-Hwan, Kim, GonSup, Ryu, Chung Ho, Shin, Sung Chul, Hong, Soon Chan, Choi, Yung Hyun, Jung, Jin-Myung
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Cancer Prevention 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189478/
https://ncbi.nlm.nih.gov/pubmed/25337568
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