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p53 Enhances Artemisia annua L. Polyphenols-Induced Cell Death Through Upregulation of p53-Dependent Targets and Cleavage of PARP1 and Lamin A/C in HCT116 Colorectal Cancer Cells

Plant-derived natural polyphenols exhibit anticancer activity without showing any noticeable toxicities to normal cells. The aim of this study was to investigate the role of p53 on the anticancer effect of polyphenols isolated from Korean Artemisia annua L. (pKAL) in HCT116 human colorectal cancer c...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Jung, Eun Joo, Lee, Won Sup, Paramanantham, Anjugam, Kim, Hye Jung, Shin, Sung Chul, Kim, Gon Sup, Jung, Jin-Myung, Ryu, Chung Ho, Hong, Soon Chan, Chung, Ky Hyun, Kim, Choong Won
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730414/
https://ncbi.nlm.nih.gov/pubmed/33297377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239315
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