Quercetin Regulates Sestrin 2-AMPK-mTOR Signaling Pathway and Induces Apoptosis via Increased Intracellular ROS in HCT116 Colon Cancer Cells

BACKGROUND: The suppression of abnormal cell proliferation is therapeutic strategies for the treatment of cancer. In this study, we investigated the regulatory mechanism of quercetin-induced apoptosis through regulation of Sestrin 2 and AMPK signaling pathway. METHODS: After treatment of quercetin t...

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Detalhes bibliográficos
Main Authors: Kim, Guen Tae, Lee, Se Hee, Kim, Young Min
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Cancer Prevention 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189461/
https://ncbi.nlm.nih.gov/pubmed/25337554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2013.18.3.264
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