Recent Advances in In Vivo Genotoxicity Testing: Prediction of Carcinogenic Potential Using Comet and Micronucleus Assay in Animal Models

Genotoxic events have been known as crucial step in the initiation of cancer. To assess the risk of cancer, genotoxicity assays, including comet, micronucleus (MN), chromosomal aberration, bacterial reverse, and sister chromatid exchange assay, can be performed. Compared with in vitro genotoxicity a...

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Bibliographic Details
Main Authors: Kang, Seung Hun, Kwon, Jee Young, Lee, Jong Kwon, Seo, Young Rok
Format: Artigo
Language:Inglês
Published: Korean Society of Cancer Prevention 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189446/
https://ncbi.nlm.nih.gov/pubmed/25337557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2013.18.4.277
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