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Combining the in vivo comet and micronucleus assays: a practical approach to genotoxicity testing and data interpretation
Despite regulatory directives requiring the reduction of animal use in safety testing, recent modifications to genotoxicity testing guidelines now propose the use of two in vivo genotoxicity assays as a follow-up to an in vitro positive (International Conference on Harmonization Consensus Draft Guid...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Oxford University Press
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825345/ https://ncbi.nlm.nih.gov/pubmed/19969526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gep060 |
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