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The Schizophrenia Susceptibility Gene Dysbindin Regulates Dendritic Spine Dynamics

Dysbindin is a schizophrenia susceptibility gene required for the development of dendritic spines. The expression of dysbindin proteins is decreased in the brains of schizophrenia patients, and neurons in mice carrying a deletion in the dysbindin gene have fewer dendritic spines. Hence, dysbindin mi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jia, Jie-Min, Hu, Zhonghua, Nordman, Jacob, Li, Zheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188970/
https://ncbi.nlm.nih.gov/pubmed/25297099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0184-14.2014
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