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Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila

The dysfunction of multiple neurotransmitter systems is a striking pathophysiological feature of many mental disorders, schizophrenia in particular, but delineating the underlying mechanisms has been challenging. Here we show that manipulation of a single schizophrenia susceptibility gene, dysbindin...

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Détails bibliographiques
Auteurs principaux: Shao, Lisha, Shuai, Yichun, Wang, Jie, Feng, Shanxi, Lu, Binyan, Li, Zuo, Zhao, Yukai, Wang, Lianzhang, Zhong, Yi
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219129/
https://ncbi.nlm.nih.gov/pubmed/22049342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114569108
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