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Dynamic Epigenetic Control of Highly Conserved Noncoding Elements

BACKGROUND: Many noncoding genomic loci have remained constant over long evolutionary periods, suggesting that they are exposed to strong selective pressures. The molecular functions of these elements have been partially elucidated, but the fundamental reason for their extreme conservation is still...

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Autors principals: Seridi, Loqmane, Ryu, Taewoo, Ravasi, Timothy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188601/
https://ncbi.nlm.nih.gov/pubmed/25289637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109326
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