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Dynamic Epigenetic Control of Highly Conserved Noncoding Elements

BACKGROUND: Many noncoding genomic loci have remained constant over long evolutionary periods, suggesting that they are exposed to strong selective pressures. The molecular functions of these elements have been partially elucidated, but the fundamental reason for their extreme conservation is still...

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Detalhes bibliográficos
Main Authors: Seridi, Loqmane, Ryu, Taewoo, Ravasi, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188601/
https://ncbi.nlm.nih.gov/pubmed/25289637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109326
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