Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations

To induce a deployable level of efficacy, a successful malaria vaccine would likely benefit from both potent cellular and humoral immunity. These requirements are met by a heterologous prime-boost immunization strategy employing a chimpanzee adenovirus vector followed by modified vaccinia Ankara (MV...

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Main Authors: Kimani, Domtila, Jagne, Ya Jankey, Cox, Momodou, Kimani, Eva, Bliss, Carly M, Gitau, Evelyn, Ogwang, Caroline, Afolabi, Muhammed O, Bowyer, Georgina, Collins, Katharine A, Edwards, Nick, Hodgson, Susanne H, Duncan, Christopher J A, Spencer, Alexandra J, Knight, Miguel G, Drammeh, Abdoulie, Anagnostou, Nicholas A, Berrie, Eleanor, Moyle, Sarah, Gilbert, Sarah C, Soipei, Peninah, Okebe, Joseph, Colloca, Stefano, Cortese, Riccardo, Viebig, Nicola K, Roberts, Rachel, Lawrie, Alison M, Nicosia, Alfredo, Imoukhuede, Egeruan B, Bejon, Philip, Chilengi, Roma, Bojang, Kalifa, Flanagan, Katie L, Hill, Adrian V S, Urban, Britta C, Ewer, Katie J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188556/
https://ncbi.nlm.nih.gov/pubmed/24930599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.109
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