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Characterization of Protein Unfolding with Solid-state Nanopores

In this work, we review the process of protein unfolding characterized by a solid-state nanopore based device. The occupied or excluded volume of a protein molecule in a nanopore depends on the protein’s conformation or shape. A folded protein has a larger excluded volume in a nanopore thus it block...

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Main Authors: Li, Jiali, Fologea, Daniel, Rollings, Ryan, Ledden, Brad
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188535/
https://ncbi.nlm.nih.gov/pubmed/24370259
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