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Regulator of G-Protein Signaling-5 Is a Marker of Hepatic Stellate Cells and Expression Mediates Response to Liver Injury

Liver fibrosis is mediated by hepatic stellate cells (HSCs), which respond to a variety of cytokine and growth factors to moderate the response to injury and create extracellular matrix at the site of injury. G-protein coupled receptor (GPCR)-mediated signaling, via endothelin-1 (ET-1) and angiotens...

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Detalhes bibliográficos
Main Authors: Bahrami, Arya J., Gunaje, Jagadambika J., Hayes, Brian J., Riehle, Kimberly J., Kenerson, Heidi L., Yeung, Raymond S., Stempien-Otero, April S., Campbell, Jean S., Mahoney, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188519/
https://ncbi.nlm.nih.gov/pubmed/25290689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108505
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