A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD

BACKGROUND: Skeletal muscle impairment is a recognized complication of COPD, predicting mortality in severe disease. Increasing evidence implicates the renin-angiotensin system in control of muscle phenotype. We hypothesized that angiotensin-converting enzyme (ACE) inhibition would improve quadricep...

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Autors principals: Shrikrishna, Dinesh, Tanner, Rebecca J., Lee, Jen Y., Natanek, Amanda, Lewis, Amy, Murphy, Patrick B., Hart, Nicholas, Moxham, John, Montgomery, Hugh E., Kemp, Paul R., Polkey, Michael I., Hopkinson, Nicholas S.
Format: Artigo
Idioma:Inglês
Publicat: American College of Chest Physicians 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188149/
https://ncbi.nlm.nih.gov/pubmed/24556825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.13-2483
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