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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders

Differentiation and activation of osteoclasts play a key role in the development of musculoskeletal diseases as these cells are primarily involved in bone resorption. Osteoclasts can be generated in vitro from monocyte/macrophage precursor cells in the presence of certain cytokines, which promote su...

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Библиографические подробности
Главные авторы: Wu, Dennis J., Dixit, Neha, Suzuki, Erika, Nguyen, Thanh, Shin, Hyun Seock, Davis, Jack, Maverakis, Emanual, Adamopoulos, Iannis E.
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188139/
https://ncbi.nlm.nih.gov/pubmed/24961167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51810
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