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Expression, purification and preliminary crystallographic analysis of the cryptic polo-box domain of Caenorhabditis elegans ZYG-1

ZYG-1 is a polo-like kinase essential for centriole assembly in Caenorhabditis elegans. The targeting of ZYG-1 to nascent centrioles is via its central cryptic polo-box (CPB) domain. To shed light on the molecular basis of ZYG-1 recruitment, it is necessary to obtain structural knowledge of the ZYG-...

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Bibliografske podrobnosti
Main Authors: Shimanovskaya, Ekaterina, Dong, Gang
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188077/
https://ncbi.nlm.nih.gov/pubmed/25286937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14016094
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