Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

Glutamine can play a critical role in cellular growth in multiple cancers. Glutamine‐addicted cancer cells are dependent on glutamine for viability, and their metabolism is reprogrammed for glutamine utilization through the tricarboxylic acid (TCA) cycle. Here, we have uncovered a missing link betwe...

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Hauptverfasser: Yang, Lifeng, Moss, Tyler, Mangala, Lingegowda S, Marini, Juan, Zhao, Hongyun, Wahlig, Stephen, Armaiz‐Pena, Guillermo, Jiang, Dahai, Achreja, Abhinav, Win, Julia, Roopaimoole, Rajesha, Rodriguez‐Aguayo, Cristian, Mercado‐Uribe, Imelda, Lopez‐Berestein, Gabriel, Liu, Jinsong, Tsukamoto, Takashi, Sood, Anil K., Ram, Prahlad T, Nagrath, Deepak
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188042/
https://ncbi.nlm.nih.gov/pubmed/24799285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/msb.20134892
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