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Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Reactive stromal cells are an integral part of tumor microenvironment (TME) and interact with cancer cells to regulate their growth. Although targeting stromal cells could be a viable therapy to regulate the communication between TME and cancer cells, identification of stromal targets that make canc...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Yang, Lifeng, Achreja, Abhinav, Yeung, Tsz-Lun, Mangala, Lingegowda S., Jiang, Dahai, Han, Cecil, Baddour, Joelle, Marini, Juan C., Ni, Joseph, Nakahara, Ryuichi, Wahlig, Stephen, Chiba, Lisa, Kim, Sun Hye, Morse, Joshua, Pradeep, Sunila, Nagaraja, Archana Sidalaghatta, Haemmerle, Monika, Kyunghee, Noh, Derichsweiler, Mathew, Plackemeier, Thomas, Mercado-Uribe, Imelda, Lopez-Berestein, Gabriel, Moss, Tyler, Ram, Prahlad T., Liu, Jinsong, Lu, Xiongbin, Mok, Samuel C., Sood, Anil K., Nagrath, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329194/
https://ncbi.nlm.nih.gov/pubmed/27829138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.10.011
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