Interaction of Interferon Gamma-Induced Reactive Oxygen Species with Ceftazidime Leads to Synergistic Killing of Intracellular Burkholderia pseudomallei

Burkholderia pseudomallei, a facultative intracellular pathogen, causes severe infections and is inherently refractory to many antibiotics. Previous studies from our group have shown that interferon gamma (IFN-γ) interacts synergistically with the antibiotic ceftazidime to kill bacteria in infected...

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Detalhes bibliográficos
Main Authors: Mosovsky, Kara, Silva, Ediane, Troyer, Ryan, Propst-Graham, Katie, Dow, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187985/
https://ncbi.nlm.nih.gov/pubmed/25070108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02781-14
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